High affinity copper uptake protein

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August undefined, 2024

Web1 de abr. de 2024 · The CTR1 gene of Saccharomyces cerevisiae encodes a protein required for high affinity copper uptake. The protein is expressed on the plasma membrane, is heavily glycosylated with O-linkages, and ... Web12 de out. de 2012 · The Ctr1 gene encodes a multispanning plasma membrane protein of 460 amino acids and is a necessary factor in high affinity copper uptake and supplies copper for all known copper-dependent physiological processes (Georgatsou et al., 1997, Sinani et al., 2007, Nakagawa et al., 2010).

X-ray structures of the high-affinity copper transporter Ctr1

WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562COPPER (I) IONZINC ION NCBI National Center forBiotechnology Information Search 6M98: Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu(I) Biological Unit for 6M98: trimeric; determined by author and by software (PISA) Web12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on the cell surface. Trojan horse antibiotics have evolved to hijack these transporters for uptake across the outer membrane (OM). birds of stewart island

UniProt

Web10 de abr. de 2024 · Abstract Heavy metal contamination impacts plant growth and productivity by causing damage at all levels of plant organization, making it one of the most significant abiotic stressors. This study evaluated the uptake and distribution of cadmium (Cd) and copper (Cu) in Solanum lycopersicum L. and identified the antioxidant enzyme … WebThe redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport, oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. However, little is known … WebAlternate Antibody Name: Alternate Gene Names: Solute Carrier Family 31 (Copper Transporter), Member 1; COPT1; CTR1; Copper Transporter 1; Solute Carrier Family 31 … danbury midwives of ct facility

6M97: Crystal structure of the high-affinity copper transporter Ctr1

High affinity copper uptake protein

RCSB PDB - 6M97: Crystal structure of the high-affinity copper ...

WebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function WebThe major human high-affinity copper uptake protein, human copper transporter hCTR1, was recently shown to be at the basolateral or blood side of both intestinal and renal ...

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Web8 de abr. de 2024 · HIGHLIGHTS. who: Nina Salustros from the (UNIVERSITY) have published the research: Structural basis of ion uptake in copper-transporting P1B-type ATPases, in the Journal: (JOURNAL) of 16/08/2024 what: Transport and regulation mechanism Based on detailed analyses of the structurally determined E1 state and … WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 …

Web15 de mar. de 1996 · Two proteins in the plasma membrane of yeast—a multicopper oxidase, encoded by the FET3 gene, and a permease, encoded by the FTR1 gene—were shown to mediate high-affinity iron uptake. FET3 expression was required for FTR1 protein to be transported to the plasma membrane. Web27 de mar. de 2024 · The high-affinity Cu transporter Ctr1 (K m ≈ 2 μM) 4, an integral membrane protein localized to the plasma membrane and endosomal vesicles, …

Web12 de abr. de 2024 · To overcome this challenge, bacteria synthesize high-affinity iron-binding molecules called siderophores, which are recognized by specific transporters on … WebProtein target information for High affinity copper uptake protein 1 (house mouse). Find diseases associated with this biological target and compounds tested against it in …

Web5 de jan. de 2024 · high affinity copper uptake protein 1, copper transporter 1, solute carrier family 13 (sodium/sulphate symporters), member 1 GeneRIFs: Gene …

High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais birds of st john usviWeb149 Likes, 9 Comments - Joshua Rubin (@realfoodgangstas) on Instagram: "10 Things You Can Do Today to Replenish Zinc Status to Support Thyroid Health Lets talk about ... danbury mint 1969 camaro ssWebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like birds of steel gameWebCopper (Cu) is an essential trace element for growth and development and abnormal Cu levels are associated with anemia, metabolic disease and cancer. Evolutionarily … danbury mint 1969 dodge charger r/tWeb11 de abr. de 2024 · To investigate whether Met44 residue in COPT1 is also sufficient for copper acquisition, we converted Met44 to alanine in the full-length COPT1 protein, and transformed this mutant allele [COPT1(M44A)] into S. cerevisiae ctr1Δctr3Δ strain which lacks high affinity copper transporters CTR1 and CTR3 and cannot grow on … danbury mint 2008 gold ornament collectionWeb5 de jun. de 2001 · Copper serves as an essential cofactor for a variety of proteins in all living organisms. Previously, we described a human gene (CTR1;SLC31A1)that encodes a high-affinity copper-uptake protein and hypothesized that this protein is required for copper delivery to mammalian cells. danbury mint 2010 gold ornament collectionWeb15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... danbury mint 2000 christmas snow globe